Marjorie Henderson Buell (December 11, 1904-May 30, 1993) was an American cartoonist who worked under the pen name Marge. She was best known as the creator of Little Lulu.
Biography on Wikipedia: https://en.wikipedia.org/wiki/Marge_(cartoonist)

The First Appearance of Little Lulu by Marjorie Henderson Buell
February 23, 1935 issue, Saturday Evening Post / Drawing / 6.5″x7″ / Private collection

Marjorie Henderson Buell on Artnet: http://www.artnet.com/artists/marjorie-henderson-buell/

Further reading:
https://www.lambiek.net/artists/m/marge.htm
https://pabook.libraries.psu.edu/literary-cultural-heritage-map-pa/bios/Buell__Marjorie
https://news.harvard.edu/gazette/story/2006/11/little-lulu-comes-to-harvard/